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1

Novel targeted siRNA-loaded hybrid nanoparticles: preparation, characterization and in vitro evaluation

Dim, Nneka, Perepelyuk, Maryna, Gomes, Olukayode, Thangavel, Chellappagounder, Liu, Yi, Den, Robert, Lakshmikuttyamma, Ashakumary, Shoyele, Sunday A.

Journal:

Journal of Nanobiotechnology

Année:

2015

Langue:

english

Fichier:

PDF, 2.07 MB

english, 2015

2

Quercetin regulates β-catenin signaling and reduces the migration of triple negative breast cancer

Srinivasan, Asha, Thangavel, Chellappagounder, Liu, Yi, Shoyele, Sunday, Den, Robert B., Selvakumar, Ponniah, Lakshmikuttyamma, Ashakumary

Journal:

Molecular Carcinogenesis

Année:

2015

Langue:

english

Fichier:

PDF, 4.18 MB

english, 2015

3

siRNA-Encapsulated Hybrid Nanoparticles Target Mutant K- ras and Inhibit Metastatic Tumor Burden in a Mouse Model of Lung Cancer

Perepelyuk, Maryna, Shoyele, Olubunmi, Birbe, Ruth, Thangavel, Chellappagounder, Liu, Yi, Den, Robert B., Snook, Adam E., Lu, Bo, Shoyele, Sunday A.

Journal:

Molecular Therapy — Nucleic Acids

Année:

2017

Langue:

english

Fichier:

PDF, 1.86 MB

english, 2017

4

Sex-dependent expression of CYP2C11 in spleen, thymus and bone marrow regulated by growth hormone

Chellappagounder Thangavel, Ravindra N. Dhir, Denys V. Volgin, Bernard H. Shapiro

Journal:

Biochemical Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 451 KB

english, 2007

5

Intrinsic sex differences determine expression of growth hormone-regulated female cytochrome P450s

Chellappagounder Thangavel, Martha C Garcia, Bernard H Shapiro

Journal:

Molecular and Cellular Endocrinology

Année:

2004

Langue:

english

Fichier:

PDF, 118 KB

english, 2004

6

RB Restricts DNA Damage-Initiated Tumorigenesis through an LXCXE-Dependent Mechanism of Transcriptional Control

Ryan J. Bourgo, Chellappagounder Thangavel, Adam Ertel, Jacqueline Bergseid, A. Kathleen McClendon, Ludwig Wilkens, Agnieszka K. Witkiewicz, Jean Y.J. Wang, Erik S. Knudsen

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2011

7

Proliferative Suppression by CDK4/6 Inhibition: Complex Function of the Retinoblastoma Pathway in Liver Tissue and Hepatoma Cells

Dayana B. Rivadeneira, Christopher N. Mayhew, Chellappagounder Thangavel, Elena Sotillo, Christopher A. Reed, Xavier Graña, Erik S. Knudsen

Journal:

Gastroenterology

Année:

2010

Langue:

english

Fichier:

PDF, 3.11 MB

english, 2010

8

Inherent sex-dependent regulation of human hepatic CYP3A5

Thangavel, Chellappagounder, Boopathi, Ettickan, Shapiro, Bernard H

Journal:

British Journal of Pharmacology

Année:

2013

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2013

9

Regulation of miR106b cluster through the RB pathway

Thangavel, Chellappagounder, Boopathi, Ettickan, Ertel, Adam, Lim, Meng, Addya, Sankar, Fortina, Paolo, Witkiewicz, Agnieszka K., Knudsen, Erik S.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 4.38 MB

english, 2013

10

A Molecular Basis for the Sexually Dimorphic Response to Growth Hormone

Thangavel, Chellappagounder, Shapiro, Bernard H.

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 338 KB

english, 2007

11

Determinants of Growth Hormone Receptor Down-Regulation

Deng, Luqin, He, Kai, Wang, Xiangdong, Yang, Ning, Thangavel, Chellappagounder, Jiang, Jing, Fuchs, Serge Y., Frank, Stuart J.

Journal:

Molecular Endocrinology

Année:

2007

Langue:

english

Fichier:

PDF, 462 KB

english, 2007

12

Intrinsic Sexually Dimorphic Expression of the Principal Human CYP3A4 Correlated with Suboptimal Activation of GH/Glucocorticoid-Dependent Transcriptional Pathways in Men

Thangavel, Chellappagounder, Boopathi, Ettickan, Shapiro, Bernard H.

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.46 MB

english, 2011

13

Biodistribution and Pharmacokinetics Study of siRNA-loaded Anti-NTSR1-mAb-functionalized Novel Hybrid Nanoparticles in a Metastatic Orthotopic Murine Lung Cancer Model

Perepelyuk, Maryna, Thangavel, Chellappagounder, Liu, Yi, Den, Robert B, Lu, Bo, Snook, Adam E, Shoyele, Sunday A

Journal:

Molecular Therapy — Nucleic Acids

Année:

2016

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2016

14

Role of microRNAs in gastrointestinal smooth muscle fibrosis and dysfunction: novel molecular perspectives on the pathophysiology and therapeutic targeting

Krishna, Chadalavada Vijay, Singh, Jagmohan, Thangavel, Chellappagounder, Rattan, Satish

Journal:

AJP Gastrointestinal and Liver Physiology

Année:

2016

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2016

15

RB Loss Promotes Prostate Cancer Metastasis

Thangavel, Chellappagounder, Boopathi, Ettickan, Liu, Yi, Haber, Alex, Ertel, Adam, Bhardwaj, Anshul, Addya, Sankar, Williams, Noelle, Ciment, Stephen J., Cotzia, Paolo, Dean, Jeffry L., Snook, Adam,

Journal:

Cancer Research

Année:

2017

Langue:

english

Fichier:

PDF, 3.16 MB

english, 2017

16

Therapeutic Challenge With a CDK 4/6 Inhibitor Induces an RB-dependent SMAC Mediated Apoptotic Response in Non-Small Cell Lung Cancer

Thangavel, Chellappagounder, Boopathi, Ettickan, Liu, Yi, McNair, Christopher, Haber, Alex, Perepelyuk, Maryna, Bhardwaj, Anshul , Addya, Sankar, Ertel, Adam, Shoyele, Sunday, Birbe, Ruth, Salvino,

Journal:

Clinical Cancer Research

Année:

2018

Langue:

english

Fichier:

PDF, 2.57 MB

english, 2018

17

Improvement in Therapeutic Efficacy and Reduction in Cellular Toxicity: Introduction of a Novel Anti-PSMA-Conjugated Hybrid Antiandrogen Nanoparticle

Thangavel, Chellappagounder, Perepelyuk, Maryna, Boopathi, Ettickan, Liu, Yi, Polischak, Steven, Deshpande, Deepak A., Rafiq, Khadija, Dicker, Adam P., Knudsen, Karen E., Shoyele, Sunday A., Den, Robe

Journal:

Molecular Pharmaceutics

Année:

2018

Langue:

english

Fichier:

PDF, 11.39 MB

english, 2018

18

Increased expression of desmin and vimentin reduces bladder smooth muscle contractility via JNK2

Javed, Elham, Thangavel, Chellappagounder, Frara, Nagat, Singh, Jagmohan, Mohanty, Ipsita, Hypolite, Joseph, Birbe, Ruth, Braverman, Alan S., Den, Robert B., Rattan, Satish, Zderic, Stephen A., Deshpa

Journal:

The FASEB Journal

Année:

2019

Fichier:

PDF, 2.58 MB

2019

19

CDK4/6 inhibition protects normal cells against cancer therapy-induced damage

Boopathi, Ettickan, Thangavel, Chellappagounder

Journal:

Translational Cancer Research

Année:

2020

Langue:

english

Fichier:

PDF, 141 KB

english, 2020